We conducted a single-dose, crossover study in six human subjects of two dosage forms of vitamin B12 – a liposomal liquid and a liposomal powder-filled capsule. Equivalent doses were given one time. Serum B12 measurements were conducted at baseline, then at 45 minutes, 75 minutes, and 135 minutes after dosing. Each subject was given 3 mg of vitamin B12 in one dosage form, followed by a washout period of 14 days, then dosing with the other dosage form.
Baseline B12 levels were, as expected, different between subjects. All subjects (with one exception) had an increase above baseline at one or more time points. Comparing the different dosage forms, the capsule performed better than the traditional liquid in five of six subjects. The one subject with an abnormally high baseline prior to liquid dosing was the only outlier.
All subjects had serum B12 increases after taking the capsule formulation at T45, then all but one had increased at T75 and T135, but not in a linear fashion. This might be due to the normal pharmacokinetics of oral vitamin B12 intake, as there is a significant and complex intestinal enterocyte uptake, transport, and enterohepatic circulation of this vitamin.
On average, the serum B12 in five of six subjects in this study increased six-fold after taking a Nutristack® Liposomal Vitamin compared to the traditional liposomal liquid when comparing the highest peak of each subject’s serum B12.
Nutristack® Liposomes are made through a completely natural process. It’s what makes us unique. Nutristack® Liposomes produced in our lab come entirely from mother nature. All supplements we produce using Nutristack® Liposomal Technology are safe, sustainable, and effective.
Pregnancy is a special time in a woman's life, but it can also be physically demanding. It's important to make sure you're getting all the essential nutrients needed to support a healthy pregnancy and fetal development. In this blog post, we've discussed some of the key nutrients that are important during pregnancy and how you can make sure you're getting enough of them.
Gut health may not be a topic that receives a lot of attention, but it is incredibly important for overall health and well-being. Your gut is home to trillions of microorganisms that help with digestion, absorption of nutrients, and even your immune system. If you are experiencing gut issues like bloating, constipation, or diarrhea, it's time to take action. Here are some lifestyle changes you can make to support a healthier gut.
When it comes to living your best life, it doesn’t always have to mean super busy days, with non-stop adrenaline, and never ending road trips. It can also mean learning how to make the most out of each day, and learning how to be a little more intentional with your time. Take a look!
'Tis the season for all things delicious, and what better way to bond and celebrate than whipping up sweets in the kitchen. Whether you're a seasoned chef or just starting out in the kitchen, these three recipes are sure to delight your taste buds and bring some holiday cheer to your home.
Get ready to capture the joy and togetherness of the holiday season with a fun and memorable family photoshoot. To help inspire your own holiday photoshoot, we've compiled a list of our top four picks for making the most of this special time of year.
Feeling overwhelmed by the holiday season as a mom? Don't let stress ruin the joy of the season - try these self-care tips that can help you take care of yourself and your family during the busy holiday season
When I became pregnant, I felt completely alone. I didn't have any mom friends, any knowledge about pregnancy or postpartum. I felt completely lost on the internet with conflicting information and it truly became overwhelming and hard to figure out how to educate myself properly; how to be able to make informed decisions while remaining calm and empowered.
Got acne problems? We can relate. A spot or two is normal but if you get bad breakouts that don't seem to go away, the problem could be hormonal. Read on to get helpful tips on which vitamins you can take to help your skin deal and heal from acne.
Have you every picked up a magazine to look at exactly what Jennifer Anniston is eating to stay in such great shape. If your answer was yes, you’re not alone! So today, we decided to talk about 3 popular diets that have powered Hollywood, but from a nutritionists perspective. Take a look.
The ultimate post-workout treat! This refreshing spiced mango smoothie is the perfect recovery smoothie after a good workout session. Not only does it help relieve joint & muscle aches, but it also just tastes incredible.
Fat has been given a bad rep for causing weight gain, however the truth is that healthy fats are an essential part of every diet, and can actually help with weight loss if necessary. Find out how you can incorporate healthy fats into your diet.
2x4 is a wellness brand created by doctors and wellness advocates. We seek to empower those who are curious about better nutrition and provide tools to multiply wellness.