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Naturally & Ethically Sourced

Ingredients You Can Trust

All our ingredients are traceable to their natural points of origin. We’re committed to creating reliable and transparent solutions for your well-being.

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  • Vitamins Vitamins
  • Minerals Minerals
  • Herb Herb
  • Other Nutrients Other
ingredients vitamin c

Vitamin C is a key mineral needed to strengthen immune function, boost collagen production, reduce inflammation in the body, and promote healing. It is necessary for the growth, development, and repair of body tissue, and it protects against oxidative stress and enhances white blood cell function. However, Vitamin C is a water-soluble vitamin and cannot be stored in the body. Hence, a sufficient amount of Vitamin C must be consumed daily.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Beautiful Glow™, 2x4 Men's Multi™, 2x4 Resilient-C™, 2x4 Stress Relief™, 2x4 Total Immunity™, 2x4 Women's Multi™,

ingredients sodium ascorbate

Sodium Ascorbate is a form of ascorbic acid (Vitamin C) that can help reduce oxidative stress, provide immune support, and aid in collagen production.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Resilient-C™, 2x4 Total Immunity™, 2x4 Stress Relief™,

ingredients vitamin d3

Vitamin D3 (also known as Cholecalciferol) is a form of Vitamin D. When vitamin D3 is consumed, it is converted into the main form of vitamin D that helps the body absorb calcium for bone health, provides immune support, and regulates mood and energy levels. Vitamin D3 is a fat-soluble vitamin that is naturally produced through exposure to sunlight, can be consumed through certain foods such as egg yolks and salmon, and can be taken through essential vitamins and supplements.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Immune Strength™, 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

ingredients vitamin k2

Vitamin K is a fat-soluble vitamin that our body needs for proper blood clotting, calcium absorption, and bone building. It is found in high amounts in leafy greens such as kale, spinach, and broccoli.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™, 2x4 Immune Strength™,

ingredients zinc

Zinc also known as zinc gluconate - is an essential nutrient that is critical for the proper development and function of immune cells, as well as in DNA synthesis, protein production, and wound healing. Zinc is another mineral that your body cannot naturally produce. Hence daily consumption of Zinc through diet and supplementation is essential.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Beautiful Glow™, 2x4 Cold Reducer™, 2x4 Total Immunity™, 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

ingredients turmeric curcumin

Turmeric Curcumin has been used in India for thousands of years as both a spice and medicinal herb. It contains compounds, known as curcuminoids, that have been shown to support your body's natural anti-inflammatory response.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Joints & Muscles™,

ingredients magnesium

Magnesium is an essential natural mineral that is required for over 300 biochemical reactions in our body. It helps regulate blood sugar levels and the activity of certain enzymes, which is important for the proper functioning of muscles and nerves, protein synthesis, bone health, and nutrient transport.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™, 2x4 Whole Body Calm™,

ingredients coq10

CoQ10 is a naturally occurring nutrient that is created and stored in the mitochondria of the cells. It helps generate energy by creating ATP and serves as a powerful antioxidant that protects the body from oxidative stress and disease causing bacteria and viruses. As you age, CoQ10 levels naturally decrease. Yet, it is a compound needed to produce the energy that is necessary for cells to function properly. Hence, vitamins can aid in supplying your body with the sufficient CoQ10 levels that it needs.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Heart Health™,

ingredients vitamin b12

Vitamin B12 also known as Methylcobalamin, is an essential vitamin found in a variety of natural sources. These include animal products such as fish, milk, and eggs. Vitamin B12 is required for the development, myelination, and function of the central nervous system; healthy red blood cell formation; and increased amounts can improve energy levels.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Beautiful Glow™, 2x4 Men's Multi™, 2x4 Women's Multi™, 2x4 Natural Energy™,

ingredients glutathione

Glutathione is a natural antioxidant that is produced by the liver and can also be found in various food sources such as spinach, avocados, asparagus, and okra. This essential mineral helps combat free radicals, while detoxifying chemicals and toxins in the liver. Glutathione is also involved in many other processes such as building and repairing tissues, generating essential chemicals and proteins, as well as strengthening immunity.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Body Detox™,

ingredients elderberry extract

Elderberry Extract is the dark purple berry of the European or black elder tree, which grows in the warmer parts of Europe, North America, Asia, and Northern Africa. The berries and flowers of Elderberry may have anti-viral and anti-bacterial properties and can help support your immune system during cold and flu seasons.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Total Immunity™,

ingredients astragalus root extract

Astragalus Root Extract is an herb that has been used in ancient Chinese medicine as a natural aid to help strengthen and boost immunity, as well as support inflammation in the body.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Total Immunity™,

ingredients echinacea whole plant extract

Echinacea Whole Plant Extract commonly called purple coneflower, is native to moist prairies, meadows, and open woods of eastern and central North America. Research has shown Echinacea helps regulate the immune system, optimize blood sugar levels, and has strong antiseptic and antiviral properties.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Total Immunity™,

ingredients gaba

GABA is a naturally occurring amino acid, that works as the chief inhibitory neurotransmitter. When GABA attaches to a protein in your brain known as a GABA receptor, it blocks, or inhibits, certain brain signals and decreases activity in your nervous system. Studies have shown that GABA can help relieve anxiety, reduce stress, and improve sleep. Some studies have also shown that GABA can play a role in burning fat, building lean muscle, and managing blood pressure.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Better Sleep™,

ingredients melatonin

Melatonin is a naturally produced hormone that regulates the body's wake-sleep cycle. It is produced by the pineal gland at night-time. Once produced, Melatonin is then secreted into the bloodstream and the fluid around the brain & spinal cord, and conveys signals to our body that it's time to sleep.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Better Sleep™,

ingredients lemon balm flower extract

Lemon Balm Flower Extract (Melissa officinalis) is an herb in the mint family that is native to the eastern Mediterranean region and has naturalized in many places including North America. It has a mild lemon scent and has been used as an anti-depressant and anti-anxiety treatment due to its calming properties. Its sedative effects are thought to have a calming effect on the nerves.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Better Sleep™, 2x4 Stress Relief™, 2x4 Women's Multi™,

ingredients valerian root extract

Valerian Root Extract (Valeriana officinalis) is an herb native to Europe and parts of Asia. Valerian contains a substance known as valerenic acid that is believed to affect GABA receptors in the brain. Valerian root may support GABA function, which may improve quality of sleep, and promote a sense of calm.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Better Sleep™,

ingredients vitamin a

Vitamin A is the name of a group of fat-soluble retinoids, including retinol, retinal, and retinyl esters. In the body, beta-carotene converts into vitamin A (retinol). Vitamin A works as a powerful antioxidant that protects the body from damaging molecules called free radicals. Vitamin A is an essential mineral required to support vision, immunity, and skin health

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Beautiful Glow™, 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

ingredients biotin

Biotin also known as Vitamin B7, helps convert carbohydrates, fats, and amino acids found in your food into the building blocks of protein. Biotin is often recommended to help optimize skin, hair, and nail health.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Beautiful Glow™, 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

ingredients lutein

Lutein is a type of vitamin called a carotenoid and is normally found in large concentrations around the retinas of your eyes. Lutein absorbs excess light energy and helps protect your eyes from the harmful effects of blue light. It also works as a powerful antioxidant that supports your body against harmful free radicals.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Beautiful Glow™,

ingredients ashwagandha root extract

Ashwagandha Root Extract is one of the most important herbs in Ayurveda medicine based on the Indian principles of natural healing. It is a powerful adaptogen that can help support your adrenal health and overall well-being. Ashwagandha has been used for over 3,000 years to relieve stress, increase energy levels, and improve concentration.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Men's Multi™, 2x4 Stress Relief™, 2x4 Women's Multi™,

ingredients pantethine

Pantethine is the active form of vitamin B5 also known as Pantothenic Acid. It protects cells against oxidative damage by increasing Glutathione levels - an important compound that helps fight against harmful free radicals. Pantothenic acid also helps the body utilize carbohydrates, proteins, and lipids

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Stress Relief™,

ingredients holy basil leaf extract

Holy Basil Leaf Extract is a powerful herb which research has found, contains several bioactive (medicinal) compounds. These include Eugenol (clove oil), which aids in lowering blood glucose levels, Ursolic Acid, known for its powerful antioxidant, antibacterial, and antifungal properties, and Eucaluptol, which provides immunity support.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Stress Relief™,

ingredients calcium

Calcium is the most abundant mineral in our body that, along with phosphorus, builds and maintains strong bones and teeth. Our body needs calcium for muscles to move and for nerves to carry messages between the brain and every part of the body. It also helps blood flow in our blood vessels and helps release hormones that affect many functions in our bodies.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

ingredients iron

Iron is an essential mineral used to make hemoglobin and myoglobin. Hemoglobin allows oxygen to be carried from the lungs to the body's cells, whereas myoglobin ensures your muscle tissues have adequate oxygen levels to support energy production. Iron is also used to build and maintain strong muscles, healthy skin, and strong hair.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Women's Multi™,

ingredients folate

Folate is the natural form of vitamin B9 that is present in many sources of food including vegetables and fruits. Folate assists in the production of red and white blood cells, which supports the transport and distribution of oxygen throughout the body. By doing so, it aids in supporting your immunity, nerve health, and cell division.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

ingredients beet root extract

Beet Root Extract is packed with glutathione - a powerful antioxidant that helps promote liver function and overall gut health - as well as nitrates, fiber, folate, and even protein. Nitrates improve blood flow by relaxing the blood vessels and promoting dilation. They also support the body in managing blood pressure, reducing muscle aches, and promoting recovery. Fiber and folate are also great for digestion and gut health.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Men's Multi™,

ingredients betaine

Betaine is a modified amino acid that stabilizes your cell membranes and helps break down homocysteine in the body. This helps prevent cholesterol from accumulating on arterial walls. Betaine protects the liver from damage caused by toxic substances in the blood and works to protect the liver from oxidative stress and damage.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Men's Multi™,

Vitamin E

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Thiamin

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Riboflavin also known as Vitamin B2, is one of the 8 B vitamins that work together to support a number of vital bodily functions. You can get riboflavin naturally from bacteria in your gut, but it's normally not enough to meet your dietary needs. Riboflavin supports your body metabolize fats, carbohydrates, and proteins. It also works as an antioxidant that helps fight oxidative stress.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Niacin also known as vitamin B3, is a water-soluble vitamin that is needed to support energy production, as well as the proper functioning of all body cells. More than 400 enzymes require Niacin to help catalyze reactions in the body, such as the production of hormones, control of gene expression, and cellular communication.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Pantothenic Acid

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Iodine

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Selenium

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Manganese

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Chromium

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Molybdenum

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Kids Multi™, 2x4 Men's Multi™, 2x4 Women's Multi™,

Andrographis Extract (Andrographis paniculata) is an herb long used in traditional Chinese medicine and Ayurveda. Ayurveda is based on the notion that good health depends on the balance between mind, body, and spirit. Andrographis is a bitter-tasting herb rich in compounds known as andrographolides. These compounds are thought to have anti-inflammatory, antiviral, and antioxidant properties.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Total Immunity™,

Copper

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Beautiful Glow™,

Zeaxanthin

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Beautiful Glow™,

Rhodiola Root Extract has a long history of medicinal use in Russia, Scandinavia, and other parts of Europe. It is recognized as an adaptogen, which is a natural compound that helps the body adapt to and resist physical, chemical, and environmental stress. By promoting a relaxed state of physical, mental, and emotional well-being, Rhodiola promotes restful sleep and restores mental performance. Rhodiola Rosea has been shown to reduce fatigue during exercise and promote strength and energy.

Source: | Processed: | Manufactured: Colorado, USA

Products: 2x4 Stress Relief™,

Ethically Sourced, Molecularly Crafted

Made in the USA, we source our ingredients from the best suppliers around the world and blend them with our Nutristack® technology.

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Bottled with Love & Care
Peer-Reviewed Clinical Study
2x4 Resilient-C™
2x4 Resilient-C™
2x4 Resilient-C™
Builds a strong
immune system
Vitamin C
2x4 Resilient C is designed to provide a strong, multi-functional source of Vitamin C. It can offer a boost of energy to your morning routine and works throughout the day as a potent antioxidant protecting your cells against oxidative damage, boosting collagen production and protecting your immune system.
2x4 Body Detox™
2x4 Body Detox™
2x4 Body Detox™
Detox and
restore
Glutathione
2x4 Body Detox is a powerful Glutathione supplement that provides multiple health benefits for people of all ages. Glutathione can help the liver metabolize harmful chemicals supporting your body’s natural detoxification processes. It can also aid in tissue building and repair, and protects energy creating cells leading to better athletic performance and overall wellness.
2x4 Heart Health™
2x4 Heart Health™
2x4 Heart Health™
Maintain a strong
and healthy heart
CoQ10
Help your body generate energy and fight free radicals with 2x4 Heart Health, the most powerful CoQ10 supplement available. Heart Health can help exercise performance by reducing muscle fatigue and helping produce energy. Its antioxidant powers also help maintain cells healthy and young as you age.
Clinical Study
2x4 Natural Energy™
2x4 Natural Energy™
2x4 Natural Energy™
Boosts energy
levels
Vitamin B12
Supplement your Vitamin B12 intake with 2x4 Natural Energy. An essential vitamin needed for the formation of red blood cells and proper nerve function vitamin B12 can help you avoid feelings weakness and tiredness by increasing energy levels. 2x4 Natural energy can also provide support for bone health, mood balancing, and cognitive function.
Frequently Asked Questions
2x4 sources all its ingredients from all over the world, finding the best quality for our solutions. We choose our ingredients based on multiple factors, such as a region's soil quality and sustainability practices. 
Yes! Our 2x4 solutions only use 100% natural ingredients that have been ethically sourced from around the world. In addition, all of our solutions are sugar-free, gluten-free, and non-GMO. 
No, 2x4 solutions do not contain any artificial preservatives. It's why it must be refrigerated right after opening and best consumed within 30 days.
Yes, 2x4 solutions are non-GMO. Additionally, they are sugar-free and gluten-free. 
Yes, 2x4 solutions are vegan, non-GMO, sugar-free, and gluten-free. 
No, 2x4 solutions do not contain sugar or gluten. 
If you're pregnant or breastfeeding, it's best to consult with your doctor prior introducing 2x4 solutions into your regimen.
2x4 manufactures its solutions in Fort Collins, Colorado. 
All of our 2x4 packaging is recyclable. We're constantly working together with our manufacturing facility to find new ways to make our packaging more sustainable and environmentally-friendly. 
If you are looking to boost your immunity, we recommend trying 2x4 Total Immunity™ and 2x4 Immune Strength™. The key ingredients in these solutions that optimize your natural immune response include Zinc, Vitamin C, Vitamin D3, Vitamin K2, Elderberry, Astragalus Root, Echinacea, and Andrographis. 
To tackle issues with sleep and stress, we recommend coupling 2x4 Whole Body Calm™ with 2x4 Better Sleep™. These two 2x4 solutions will allow your mind to settle and help ease your body into a more peaceful, restful night's sleep. The key ingredients in these products include Magnesium, GABA, Melatonin, Lemon Balm, and Valerian Root. 
2x4 solutions are liposmal, meaning their absorption rate is much higher than average supplements, gummies, and pills. As such, your body requires smaller amounts of the same ingredients in order for you to attain your daily nutritional needs. 
Absolutely! All 2x4 solutions are made using Nutristack Technology, which is optimized for stacking or pairing. Nutristack Lipsomal technology is our patented 2-step delivery process that allows your body to absorb 95% of the nutrients found in your 2x4 solutions. First, our Nutristack technology wraps the nutrients inside tiny, microscopic bubbles that mimic your body's cell membranes. These bubbles are known as Liposomes. Then, the Nutristack delivers those nutrients directly into your bloodstream and through your cell membranes without losing any of the nutrients inside. This increases the bioavailability of our solutions by over 15x, making them the most absorbing and effective supplement available. 
Yes! We highly recommend mixing your 2x4 solutions with your favorite beverage-- be it a glass of juice, a smoothie, or tea. 2x4® solutions pairs well with any hot or cold beverage. Mix in 2x4 solutions by hand, never in a blender. This will degrade the liposomes, which is what makes these supplements more bioavailable than traditional supplements, gummies, or pills.